Gene detail

Gene detail information of Glyur000434s00017221.1

Functional Annotation

Database	Orthologs	E value	Annotation
TAIR	AT3G23890.2	0	topoisomerase II
NR	XP_004499912.1	0	PREDICTED: DNA topoisomerase 2-like [Cicer arietinum]
COG	YP_003474154.1	2.00E-42	DNA gyrase subunit beta [Thermocrinis albus DSM 14484]
Swissprot	tr\|O24308\|TOP2_PEA	0	DNA topoisomerase 2
trEMBL	tr\|I1MJQ7\|I1MJQ7_SOYBN	0	DNA topoisomerase 2 {ECO:0000256\|RuleBase:RU000381}

Sequence

Transcript Sequence

>Glyur000434s00017221.1
ATGGAGAAGCGGCCCCTCCAGAACAGCAACGCGGCGAACATCCCCACCGCGGGGAAAACGATCGAGGAGATGTACCAGAAGAAGACGCAGCTGGAACACATCCTTCTCCGACCCGACACCTACGTTGGATCCATCGAGAAGCACACGCAGTCACTGTGGGTCTACGAGAACGACGAGATGGTACACCGTTCCGTTTCCTACGTCCCAGGACTCTACAAGATCTTCGACGAGATCCTCGTCAACGCCGCTGACAACAAGCAGCGAGACCCTTCCATGGACTCCCTCAAGGTCCTCATCGATCCCGAAGCGAACGTCGTCTCCGTCTACAATAACGGAGATGGCGTCCCCGTGGAGATCCACCAGGAGGAGAAGGTCTATGTCCCTGAATTGATCTTCGGACACCTCCTCACTAGTAGCAACTACGATGACAATGTCAAGAAGACTACTGGTGGACGTAACGGCTATGGTGCCAAGCTCACTAACATCTTCTCCACCGAGTTCGTCATTGAGACCGCCGATGGCAAGCGCTTGAAGAAGTACAAACAGGTGTTTTCCGACAATATGGGGAAGAAGTCTGAGCCGGTGATAACGAAATGCAAAGAGGGTGAGAACTGGACGAAGGTAACTTTCAAGCCGGACTTGGAAAAGTTCAAAATGACCTACCTTGAAGAAGATGTTGTTGCTTTGATGAAAAAGCGTGTGTTGGACATGGCCGGGTGCCTTGGAAAGGCTGTTAAGGTTGAACTCAATGGCAAGTTGATTCGTATTAAGTCGTTTCGTGATTACGCTGATCTCTACCTGAAATCTGCCGAGAAGTCCAGACCAGTGCCCCTCCCAAGGATTCATGGCAAAGTAGGTGATAGGTGGGAGATTTGCGTGAGTTTAAGTGATGGGCAGTTTCAACAGGTCAGCTTTGTTAATTCCATTGCTACAATCAAGGGTGGGACTCATGTTGATTACGTCACCAATCAGATTACCGCCTTTGTGATGAATAAAGTAAATAAGAAGAAAAAGGATGCCAATGTCAAAGCTCACAATGTGAAGAATCATTTATGGGTTTTCGTCAATGCTCTTATTGACAACCCTGCTTTTGATTCTCAAACTAAGGAGACTCTCACGACCAGACAAGCTAGTTTTGGTTCTAAATGCGATGTTCCGGAGTCGATGCTGAAGGAAGTTGCAAATTCTGGAATAGTGGACACCCTCCTATCATGGGCAGATTTTAAGCAAAGTAAAGATTTGAAGAAAACTGATGGAACNAAGACTCAGAGAATTCGTGGGATCGTAAAGCTAGAGGATGCCAATGATGCTGGGGGAAGGAATTCTGACAAGTGTACCTTGATATTGACAGAGGGAGATTCTGCCAAGGCCCTTGCCATGGCTGGGCTCTCTGTCGTGGGTCGAGACCATTATGGGGTGTTTCCATTGAGAGGNAAATTGCTCAATGTACGGGAAGCTAGCAGTAAACAGATAATGGATAATGAAGAAATTCAAAATATAAAGAAGATCCTTGGACTGCAGCAAAACAAAGAGTACACAAGCGTAAAGTCTTTGAGATATGGTCATTTGATGATTATGGCTGANCAGGATCATGATGGCTCTCACATCAAGGGGCTGCTGATAAACTTTATTCATTCGTTCTGGCCGTCTCTGTTAAAAGTTCCAACTTTCATGGTTGAGTTTACCACTCCCATAATAAGGGCTTTTCATTCAAACGGGACAAAAATATCATTTTATTCCATGCCCGAATATGAATCATGGAGAGAAAGCTTGGGGAATAATGCAAATGGTTGGAAGATAAAGTACTATAAGGGGTTGGGTACAAGTACTCCTCAGGAAGGGAGAGAGTACTTTAGAGATCTTGATAAGCANAGGAAAGACTTCGTTTGGGAAGATGAGCTCGATGGAAATGCAATTGAGCTGGCATTCAGTAAGAAAAAGGCTGAAGATAGGAAGACCTGGATTCGTAATTTTGAGCCTGGCACATATCGTGATCATTCAGCCAGTCTTATAAACTACAAGGACTTTGTTAACAAAGAGCTTATATTGTTCTCTAGGGCGGATCTTCAAAGGTCCATTCCTTCTATGGTTGATGGCCTCAAGCCTGGTCAAAGAAAGATTCTTTTCTGCTCATTTAAGAAAAAGCTGTACAAAGAAATAAAAGTTGGNCAATTTATTGGTTATGTGTCTGAGCACTCCGCTTACCACCATGGTGAGCAAAGTCTATCTAGCACAATTATTAACATGGCACAGGATTTTGTGGGTAGCAACAACATCAATCTTCTCAAACCTAACGGTCAATTCGGTACTCGTAACTTGGGAGGTAAAGATCATGCAAGTGCCAGATACATCTACACGGAGCTAAATTCTGTTACTCGGTGCCTCTTCCATGAGGATGACGACAAGCTTCTTGAATACTTAAATGAGGATGGAAAGTCAATAGAACCGAACTGGTACATCCCGATTATACCTTTGGTTCTTGTCAATGGTAGTGAGGGAATTGGGACAGGTTGGAGTTCTTACATTCCCAATTATAATCCACGGGACATCATTGCCAATGTTAGGCGATTGTTGAATGGTGAAACAATGTTGCCAATGGATCCATGGTACAGAGGATTCAAAGGAACCATTGAGAAAAGNGCCAAGGAAGGTGGGTATGTAGTCAATGGCACAGTAGTGGAGATAGATGAGCAAACTTTTAGGATCACAGANCTGCCTATCCGTAAGTGGACTCAAGATTATAAGCAGTTCCTTGAATCTATAACTGATGGGACACCTAATGTCAAGGATCCTATCATTGAGGATTTCAGGCAGAATGGGGATGACGCAATTGTAGACATAGAAGTCAGGTTGAAGCTGGACAAAGTAGCGATGGTCATGCAAGAAGGACTGTTTAAGAAATTTAAATTGACTAGCACTATTAGCACAAGTAACATGCATCTTTTTGACGCAGAGGGGAAAATTAAGAAATATGACAATCCAGAACAAATTCTCGAAGAGTTCTTTCCACTTCGGCTGGAGTATTANGAGAGAAGAAAGAAACATATACTGGCCAACCTTGAACGACTTCTATTGGTGTTGGACAACAAAGTGAGGTTTATATTGGGGGTTGTGAACGGAGAGATTATTGTGAGCAACAGGAAAAAAGCTGATCTGTTGATGGAGCTGCAGCAGAAAGGCTTTACTCCCATGCCGAGGAAAGGCAAATCTGAAGAACCGCAAGTTGCTGGGGCAAATGATGACAATTCAGAAGAGCAGGAAGATCAGGAAAATGGGNCTGAGCCTGTCAGTGTTGAAGGAGCAAAACGGGGTGACTACGAGTATCTGTTATCCTTGCCTATTGGAACATTGACCATCGAAAGTGTTCAGAAGCTGCTAGATGAAAAGGATGAAAAGGCAAAGGAGTTTGAGATTTTGAAGGCAACACCAACGAAGTCTATGTGGATGAAGGATCTAGATGAGTTTGAAAAGAAACTTGATGAACTAGATAACAAAGAGGCAGAAGAGGAACGGAAGAGATCCAGTCAAGCAAATAAAAAGACAGGATTTGCTACAAAAGCCGCAAAGAAGCCGCCACAACCACGAAAGAATACTAAGAAGACCAAAAATGTTGAGCCAGAGAATGACAATTCTTCTATGGAAATTGAGAATGCTGTTGAAGTCACTAAACCGAAAGGCAGAGCAGGTTCTAAGAATATCCAGAAGGATGCTGATGACGAAATTCTCTCTCTTCAAGAACGCCTAGCTGCATATAACTTCGGGACCTCAAGTGATCAATCTGGAGCAATGGAAACTGAAGAACCCCCTGTGCCTGCTGGGAAGAAACAGAATAANAGAAAGGGTGGTGCAAAAAAGAAGTCCTCAAGTACCATTGTGTTGGATGATAGTGATGATGAAGGTAATGATGTTGATGACGGCGAGGATGAGGACTTTGAAGTCCTGCAGCAAGCTGCCCCAGAAGGCGGGAAAAAGAAGGGAGGGAGAAAGCCTGCAGCTGCCAAGAAGGCACCTGCAGCCACCACCAAGAAGAGAAATGTAGGCGGCAAAAAATCTCAGGCATTGAGTCAAAAGCTTATAACTGAGATGTTGCAGCCAACTGAAAGTACAGGGGCATCACCAGAGAAGAAAGTGAGGAAGATGAGGGAGTCTCCATTTAACAAGAAAAGTGGTTCTATTCTGGGCAGGGCTGCTGCTGACAAAGATAAAAGTGCAAGTGATGATTTGTCGCTGGGTTCTGCGTTCTTCTAACTCTCCTCCTAGCGCAGAGGAGGCGGTGGTTGAGGTTGCAGCACCAGCAGGAAGGCTAGACCTCAGAGGGCCAATCGTACGCGAGCAACATATGTGATAAGTGAATCCGAGAGTGACAACGATTCGGATGATAATGCTGATTTTTCTGATTTTGAAGATGATGACTAGACTATTCCCTAATAATATGTGTAGAAACTTGATCTGCGTCTTGCGGATTTTCAATTGTATTAGCATGGATGAATCAGATTCATGAATTACGTT

Protein Sequence

>Glyur000434s00017221.1
MEKRPLQNSNAANIPTAGKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQSLWVYENDEMVHRSVSYVPGLYKIFDEILVNAADNKQRDPSMDSLKVLIDPEANVVSVYNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSEPVITKCKEGENWTKVTFKPDLEKFKMTYLEEDVVALMKKRVLDMAGCLGKAVKVELNGKLIRIKSFRDYADLYLKSAEKSRPVPLPRIHGKVGDRWEICVSLSDGQFQQVSFVNSIATIKGGTHVDYVTNQITAFVMNKVNKKKKDANVKAHNVKNHLWVFVNALIDNPAFDSQTKETLTTRQASFGSKCDVPESMLKEVANSGIVDTLLSWADFKQSKDLKKTDGTKTQRIRGIVKLEDANDAGGRNSDKCTLILTEGDSAKALAMAGLSVVGRDHYGVFPLRGKLLNVREASSKQIMDNEEIQNIKKILGLQQNKEYTSVKSLRYGHLMIMAXQDHDGSHIKGLLINFIHSFWPSLLKVPTFMVEFTTPIIRAFHSNGTKISFYSMPEYESWRESLGNNANGWKIKYYKGLGTSTPQEGREYFRDLDKXRKDFVWEDELDGNAIELAFSKKKAEDRKTWIRNFEPGTYRDHSASLINYKDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCSFKKKLYKEIKVGQFIGYVSEHSAYHHGEQSLSSTIINMAQDFVGSNNINLLKPNGQFGTRNLGGKDHASARYIYTELNSVTRCLFHEDDDKLLEYLNEDGKSIEPNWYIPIIPLVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLNGETMLPMDPWYRGFKGTIEKXAKEGGYVVNGTVVEIDEQTFRITXLPIRKWTQDYKQFLESITDGTPNVKDPIIEDFRQNGDDAIVDIEVRLKLDKVAMVMQEGLFKKFKLTSTISTSNMHLFDAEGKIKKYDNPEQILEEFFPLRLEYXERRKKHILANLERLLLVLDNKVRFILGVVNGEIIVSNRKKADLLMELQQKGFTPMPRKGKSEEPQVAGANDDNSEEQEDQENGXEPVSVEGAKRGDYEYLLSLPIGTLTIESVQKLLDEKDEKAKEFEILKATPTKSMWMKDLDEFEKKLDELDNKEAEEERKRSSQANKKTGFATKAAKKPPQPRKNTKKTKNVEPENDNSSMEIENAVEVTKPKGRAGSKNIQKDADDEILSLQERLAAYNFGTSSDQSGAMETEEPPVPAGKKQNXRKGGAKKKSSSTIVLDDSDDEGNDVDDGEDEDFEVLQQAAPEGGKKKGGRKPAAAKKAPAATTKKRNVGGKKSQALSQKLITEMLQPTESTGASPEKKVRKMRESPFNKKSGSILGRAAADKDKSASDDLSLGSAFF

Location information (JBrowse)

Scaffold	Start	End	Strand
Scaffold00434	65092	72046	+

Gene family

Gene family	subfamily
--	--

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID
K03164	TOP2	EC:5.99.1.3	Platinum drug resistance	map01524

Gene Ontology

biological_process

GO:0006259 DNA metabolic process

GO:0006265 DNA topological change

molecular_function

GO:0003677 DNA binding

GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity

GO:0005524 ATP binding

Pfam domain

Protein	Pfam accession	Pfam name	Alignment start	Alignment end	E-value
Glyur000434s00017221.1	PF02518.21	HATPase_c	69	214	4.50E-06
Glyur000434s00017221.1	PF00204.20	DNA_gyraseB	259	416	2.40E-34
Glyur000434s00017221.1	PF01751.17	Toprim	447	561	3.50E-11
Glyur000434s00017221.1	PF00521.15	DNA_topoisoIV	691	1153	1.20E-122

Expression pattern

SRP053019

SRA Experiment	Description	TPM
SRR1783599	control	6.471
SRR1783600	control	6.585
SRR1783602	moderate drought stress	4.283
SRR1811619	moderate drought stress	4.205

DRP000996

SRA Experiment	Description	TPM
DRR006519	Root Summer glycyrrhizin high producing strain	8.883
DRR006520	Root Summer glycyrrhizin high producing strain	8.858
DRR006521	Root Winter glycyrrhizin high producing strain	0.300
DRR006522	Root Winter glycyrrhizin high producing strain	0.317
DRR006523	Root Summer glycyrrhizin low producing strain	2.376
DRR006524	Root Summer glycyrrhizin low producing strain	2.395
DRR006525	Leaf Summer glycyrrhizin high producing strain	1.198
DRR006526	Leaf Summer glycyrrhizin high producing strain	1.267

SRP065514

SRA Experiment	Description	TPM
SRR2867873	Salt Stress (root)	38.849
SRR2868004	Drought Stress (root)	17.829
SRR2967015	Control (root)	21.427

SRP215420

SRA Experiment	Description	TPM
SRR9715738	Leaf	5.984
SRR9715740	Leaf	0.424
SRR9715741	Leaf	1.218
SRR9715739	Root	0.580
SRR9715742	Root	3.536
SRR9715743	Root	3.104

SRP188776

SRA Experiment	Description	TPM
SRR8749027	MeJA induced 9h	34.397
SRR8749028	MeJA induced 9h	36.513
SRR8749029	MeJA induced 9h	20.224
SRR8749030	Uninduced	1.373
SRR8749031	Uninduced	0.970
SRR8749032	Uninduced	3.331

SRP175571

SRA Experiment	Description	TPM
SRR8400026	NaCl treatment - Root	22.689
SRR8400027	Control - Root	16.583